Antibiotic resistance in Croatia in 2018

Every year approximately 33000 people die in Europe of infections caused by multiplyresistant bacteria, which corresponds to a destruction of an aircraft almost every third day. About three quarters of such infections are associated with health care and the fact is that many of them could be prevented by good implementation of hospital infection control measures. However, the main driver of resistance is the use of antibiotics primarily in human medicine, but also in veterinary medicine and the environment. This is why the antibiotic resistance problem is addressed through the „One Health“ approach. This publication contributes to a joint discussion by providing human medicine data and enables comparison with data from the veterinary sector. The data from this publication are the basis for the development of local and national guidelines and the public campaigns, activities coordinated by the Interdisciplinary Section for Antibiotic Resistance Control (ISKRA). Along with the basic monitoring of the susceptibility of the most common bacterial species from all clinical isolates, dana on specific agents such as Mycobacterium tubeculosis, invasive isolates and recently gonococci are also included in this publication. Data on ambulatory and hospital antibiotic consumption are also an important part of this publication and allow an analysis of the correlation between antibiotic consumption and resistance development. Due to the use of the same methodology through a long period of surveillance it is possible to monitor and observe interesting trends in consumption and resistance. An integral part of the publication is the report on isolates that are retested in the reference laboratory because they demonstrate rare or unusual phenotype and this provides an opportunity to timely detect the emergence of new or the spread of known resistance mechanisms. A large number of tested isolates, the standardized sensitivity testing methodology and the results of the regular external quality control scheme that are discussed in this publication, guarantee the reliability of the data collected. Collection of these data is a part of the Croatian national antibiotic resistance control program, but without further action based on this information, it will be difficult to rationalize antibiotic prescribing and a desired reversion to sensitivity of key antibiotics will be difficult to achieve. Part of the activities described here are also key components of antimicrobial stewardship (AMS) programs, which are increasingly complemented by point prevalence studies on antibiotic prescribing. More and more institutions are establishing official antibiotic stewardship teams, the so-called A teams, as numerous activities aiming to rationalize antibiotic prescribing require expertise, dedication and time to perform the tasks and thoroughly analyze the data collected locally. Along with analyzing local trends, taking part in this surveillance allows comparison with other center 

Arjana Tambić Andrašević

President of the Committee for Antibiotic Resistance Surveillance in Croatia 

Report on Antibiotic Resistance in Croatia in 2018.pdf

Report on Antibiotic Resistance in Croatia in 2017.pdf

Report on Antibiotic Resistance in Croatia in 2016.pdf

Report on Antibiotic Resistance in Croatia in 2015.pdf

Report on Antibiotic Resistance in Croatia in 2014.pdf

Report on Antibiotic Resistance in Croatia in 2013.pdf

Report on Antibiotic Resistance in Croatia in 2012.pdf

Report on Antibiotic Resistance in Croatia in 2011.pdf

Report on Antibiotic Resistance in Croatia in 2010.pdf

Report on Antibiotic Resistance in Croatia in 2009.pdf

Report on Antibiotic Resistance in Croatia in 2008.pdf

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